Pharmaceutical product



Patented June 15, 1926.

HANS LANGER, OF IBERLIN-GHARLOTTENBURG, GERMANY, ASSIGNOR, TO ACTIEN GESELLS CHAFT Fill}. ANILIN FABRIKATION, 0T1 BERLIN, GERMANY.

PHARMACEUTICAL ?ROIDUGT.

No Drawing. Application filed. June 17, 1924, Serial No. 720,699, and in Germany Gctober 20, 1923.

Cou'ipounds of hexamethylenetetramine and hydrochloric acid are unknown and it is impossible to prepare stable solutions of hexarnethylenetetramine containing hydro chloric acid as he ;amethylenetetramine soon is destroyed under such conditions. But the el fiect of hexamethylenetetraminc as dis intectant for urinary organs is increased if besides it a hydrohalogenic acid is taken. Therefore, it is desirable to combine hexamethylenetetramine with hydrohalogenic acid.

riccording to the invention stable pharmaceutical products are obtained, acting when used as hexamethylenetetramine and a hydrohalogenic acid. They consist of a mixture containing heXamethylenetetramine and a halide oi an amino fatty acid compound. 'Qhese mixtures of hexamethylenetetramine and halides of amino fatty acids, for example glycocoll, alanine, as Well as their derivatives, such as their lactal'ns and esters, may be kept in the dry state, in the form of powder and equally compressed, Without decomposition. Instead of hexamethylenetetraniine its salts may be employed and to the mixtures other materials may he added.

In order to illustrate in what manner the preparations are made up! the following examples are given, Without limiting the invention, the parts being by weight: 7

1. 1 part o't hexamethylenetetramine and 1 part of alanine l'iydrochloride are mixed.

1 part of l1exa1nethylenetetramine and 3 parts of het-aine hydrohromide are equally mixed. From the powder tablets may be pressed.

3. 1 part of hexamethylenetetramine and 2 to a parts of betaine-hydrochloride are mixed.

4. 3 parts of hexamethylenetetramine, 3 parts of lactose and 8 parts of hetaine hydro chloride are mixed together.

5. 1 part of hexamethylenetetraminetriborate is mixed With 2 parts of betaine hydrochloride. v

6. 1 part of henamethylenetetraminesulfosalicylate is mixed with 2 parts of betainehydrochloride.

Having now described my invention What I claim is,

1. Pharmaceutical product consisting of a mixture containing hexamethylenetetramine and a hydrohalogenide of an amino fatty acid compound.

Pharmaceutical product consisting of a miiiture containing hexa-methylenetetramine and a lialogenide of an amino fatty acid lactam.

3. Pharmaceutical product consisting of a mixture containing hexainet-hylcnetetramine and a hydrohalogenide of betaine.

4. Pharmaceutical product consisting of a mixture containing hexamethylenetetraminc and betaine hydrochloride.

In testimony whereof I atilx my signa ture.

HANS LANGER. 

